A game I play is tying the hit counts on my AO3 page to historical meaning. Right now we’re at 1666, the second year of the Great Plague of London, which was the last major outbreak of plague, bubonic and pneumonic, on the way to the end of the epidemic in 1750. Roughly 100k people died in London over two years, which is ghastly and tiny compared to how many people died of it earlier. Plague outbreaks would continue for almost another century, and in the modern day a few people die of it every year. Some epidemic pathologists think there may be a cell in the American Southwest, New Mexico, Arizona, possibly Utah, Nevada, and Colorado, and we do have a few fatalities most years.